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Characterized by a unique imidazole ring structure, EGT has potent antioxidant and anti-inflammatory properties and selectively accumulates in highly metabolic tissues such as the brain, kidneys, and retina

Recently, the endothelin converting enzyme-2, localized in endosomes, was shown to modulate recycling of DOR by degrading opioid peptides such as deltorphin II or the opioid peptide bovine adrenal medulla 22 (BAM22), a cleavage product of proenkephalin (Gupta et al., 2014)

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If necessary, consult with your healthcare provider to adjust your treatment plan and ensure youre getting the most out of your therapy