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Sreeraj, H., et al
10.1038/s41591-019-0495-2 34 DianeA.AllouchA.Mu-U-MinR
Nazifi 2011)
Complexation of Al(III) with reduced glutathione in acidic aqueous solutions
The mechanism of doxorubicin actions involves an anticancer effect by intercalation into the DNA to inhibit DNA replication and transcription, and the inhibition of topoisomerase II, an enzyme important for DNA replication
One or more interactions may be part of the proposed antioxidant mechanism of CCM, like neutralizing or scavenging free radicals, preventing oxidative cascades, quenching oxygen, inhibiting oxidative enzymes, and deactivating toxicants oxidative properties (Rao 1994
