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Additionally, a 7-year prospective study found that while NSW alone was not significantly associated with chronic pain or CRP levels, the combination of NSW and moderately elevated CRP was associated with an increased risk of chronic pain and pro-inflammatory background 150

Furthermore, a bioinformatics analysis revealed that GPX3 is highly enriched in fatty acid metabolism and adipogenesis in the ovary

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Meakin, P.J., et al., Susceptibility of Nrf2-null mice to steatohepatitis and cirrhosis upon consumption of a high-fat diet is associated with oxidative stress, perturbation of the unfolded protein response, and disturbance in the expression of metabolic enzymes but not with insulin resistance

Research literature suggests it may influence hormone-related signalling pathways and stress-response modulation in controlled experimental models