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Stage 4: Functional Deficiency Severe complications such as B12 deficiency anaemia, nerve damage, and cognitive decline, and common symptoms like: Constant tiredness or fatigue Pale or yellowish skin Numbness or tingling in hands and feet Difficulty walking or balance issues Mood swings, irritability, or depression Memory problems or confusion B12 deficiency hair loss reversible if treated early Swollen tongue or mouth ulcers If left untreated, the effects of vitamin B12 deficiency can include permanent nerve damage and increased risk of heart disease due to high homocysteine levels

Brain inflammation

Sylibin is the component with high biological activity and accounts for 50-70% of silymarin 14,15

A review on thermal analyses of cyclodextrins and cyclodextrin complexes

Prx3 is mainly restricted to mitochondria [52] , but is also found at the plasma membrane [53] , whereas Prx4 is found in the cytosol, the endoplasmic reticulum and as secreted protein [54]

Since it enhances growth hormone production, its prohibited in professional and competitive sports