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Potentially this would lead to increased levels of serotonin, with subsequent down-regulation of serotonin receptors and this would then also result in depression

[DOI] [PubMed] [Google Scholar] Krivic A, Anic T, Seiwerth S, Huljev D, Sikiric P

Furthermore, the main purported therapeutic action of the ampakines is an alteration of plasticity

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