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While low to moderate level of ROS acts as signal transducers participating in various biological activities, excessive accumulation of ROS without prompt and effective clearance can cause oxidative damages [2, 3]
10.3390/biomedicines9070822 97 VeljacaM.Pavi-SladoljevD.MildnerB.BrajsaK.KrnicZ.BubenikM.et al (2003)
Further research is needed to fully exploit potential targets
(2) Acute hyperglycemia has been shown to upregulate the expression of angiotensin-converting enzyme (ACE) 2 while chronic hyperglycemia reduces ACE2 expression [187]
BJOG 107 , 10221028 (2000)
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