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However, prolonged exposure of neurons to glutamate leads to cell death by elevating the intracellular Ca 2+ that subsequently generates free radicals and induces apoptosis in the neuronal cells (Ola et al., 2013)

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It is also prohibited in competitive sport: it appears on the World Anti-Doping Agency (WADA) prohibited list, and organisations including the NFL, UFC and NCAA have banned it

Single cell RNA-seq analysis identifies ferroptotic chondrocyte cluster and reveals TRPV1 as an anti-ferroptotic target in osteoarthritis