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Aortopathy includes aortic dissection, characterized by a tear of the aorta, and aortic aneurysms which are characterized by a bulge or swelling of the aorta

DOI: 10.1002/14651858.CD000950

Nevertheless, as cancer and other pathologies such as diabetes, gastrointestinal, neurodegenerative, and other diseases are related to mitochondrial dysfunction, regulation of mitochondrial homeostasis by melatonin may play a significant role in these pathologies [347]

Two clinical reviews came to a similar conclusion but also pointed out certain limitations that call for further research
Winter S, Jue K, Prochazka J, Francis P, Hamilton W, Linn L, et al

PMC 4614699
