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No sign of oxidative damage in the kidney (measured as 8-OHdG levels) and normal appearance of kidney glomeruli and tubules were found in inducible Coq7 knockout mice at 6 mo of age, despite a severe depletion of total CoQ (10% of residual CoQ levels)
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This approach offers similar advantages while avoiding potential risks to ecological balance and societal acceptance
Lancet 376 , 419430 (2010)
