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Description
20-hydroxyeicosatetraenoic acid (20-HETE), a metabolite of ADA, was recently shown to be involved in neuronal ferroptosis upon ICH induction in mice ( in vitro model of ICH (Karuppagounder et al., 2018)

This is important for people who deal with things like insulin resistance or cardiovascular disease

Even though -LA and DHLA have been proven to be potential metal chelators and are excellent antioxidants, the clinical application of -LA and DHLA has as yet not been approved by the FDA because of their adverse effects
Methionine is an essential amino acid

While effective, they can be harsh and often don't do much for deep pigment

We thank Tuanlao Wang, Yuhong Chen, Shan Jiang, Yun Hong, and members of the Li lab for constructive discussions
