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Thakur V, Dev A, Vinay K
As anthracyclines are ROS-generating drugs, one of the resistance mechanisms might be related to the ability of cancer cells to evade this insult
Thus, glutamine entry into the TCA cycle can provide metabolic intermediates for NRF2-regulated NADPH-producing enzymes, such as IDH1 and ME1
Nanoparticle toxicology
It has been found that sulfasalazine inhibits cellular ferroptosis by suppressing the activity of the heterodimeric xc- that transports GSH precursors [284]
doi: 10.1164/rccm.202103-0714OC 76 HuangJMaierCZhangYSoareADeesCBeyerCet al
