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Hyperthyroidism is relatively uncommon and affects roughly 1.2% of people in the U.S

The most common glial tumors, known as astrocytomas , originate from astrocytes

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We therefore hypothesised that the structurally flexible and less conserved D2 domain might be dispensable for maintaining S-layer assembly and engineered a mutant strain devoid of D2, named RD2 (producing SlpA RD2 )