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Taken together, the appreciable target specificity and favourable safety profile support the suitability of B-017 as a potential therapeutic agent

The significant increase in plasma vitamin B6 in many children with autism spectrum disorders [73, 76, 87, 92, 93] could potentially reflect diminished cellular uptake or inefficiency of cells to retain or store B6

4E) and Equation S1 (supporting information) 50

doi: 10.7314/APJCP.2016.17.1.15

After an additional 24 h in low nutrient conditions, cells were scraped in 400 l/well TRIzol (ThermoFisher Scientific) and stored at 80 C until shipment

Mladenov et al
