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Klapheck, 1988

4.4 Activation of the reninangiotensin-aldosterone system and disturbances in calciumphosphate homeostasis Aberrant activation of the RAAS is a critical driver of CKD progression, contributing to glomerular hypertension, inflammation, and fibrosis

The so-called mother of all antioxidants, it also helps recharge fellow fighters, including vitamins C and E

Understanding Glutathione: Nature's Master Antioxidant Glutathione is a powerful antioxidant naturally produced by our bodies

Chemical Makeup (2,3) Molecular Formula: C 400 H 625 N 111 O 115 S 9 Molecular Weight: 9117.5 g/mol Other Known Titles: Long-(arg3) insulin-like growth factor-I, Insulin-like growth factor long chain R3 Research and Clinical Studies Receptor Grade IGF-1 LR3 and Anabolic Potential Unfortunately, research on the anabolic potential of IGF-1 LR3 is lacking, as the peptide is aimed towards cell culture studies

While direct clinical trials testing PureDefense w/NAC specifically for TRPM3 dysfunction have not yet been conducted, the formula's ability to aggressively replenish intracellular antioxidants (via NAC), stabilize cellular membranes (via quercetin), and rapidly activate NK cell surveillance (via EpiCor) provides a scientifically grounded, multi-targeted approach to supporting the exact immune pathways known to be compromised in these debilitating conditions