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ART synergizes with DOX to exert potent antitumor effects

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GLU.QDS displayed superior hemolysis stability (IC=7.17 g/mL) and -amylase inhibition (IC=4.73 g/mL)

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The hypoxia alleviation via O2 production, the redox balance disruption via glutathione consumption and the reactive oxygen species generation, together would down-regulate the expression of O6-methylguanine-DNA methyltransferase under TMZ medication, which is considered as the key to drug resistance

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