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According to metadata (31 studies with a total of 4179 patients), CIPN prevalence amounts up to 68% within the first month after chemotherapy, 60% after 3 months, and 30% after 6 months [20]

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this effect is considered to play a crucial role in the pathogenesis of several psychiatric disorders such as depression, bipolar disorder and schizophrenia (Manji et al., 2012)

doi: 10.1016/0005-2760(91)90209-z

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