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Matzkin H, Barak M, Braf Z

GPx-1 is also protective against amyloid beta peptide (Abeta-toxicity), which promotes intracellular ROS accumulation and has been proposed to have a central role in neurological dysfunction in Alzheimer disease pathology (24, 81)

Furthermore, both intracellular and extracellular ROS agents have the ability to influence gene expression (Singh et al., 2019) In reaction to low quantities of H 2 O 2 , certain regulatory proteins, such as protein kinase B, can change the phosphorylation process

For this, strain BW14 (BW5/pZE-sbnAB, pCS-LsBAHD*-ScAAE-Fpoah-Scgloxdh) was constructed, and as expected the -ODAP titer was increased to 229.5 9.3 mg L 1 with the accumulation of 386.3 23.7 mg L 1 L -DAP