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We speculate that because energy metabolism is dependent on NAD + and its reduced form NADH, a decline in the total NAD + content will lead to depressed energy metabolism, and NAD + supplementation will prevent that

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[DOI] [PMC free article] [PubMed] [Google Scholar] 51.Gopinath VS, Rao M, Shivahare R, Vishwakarma P, Ghose S, Pradhan A, Hindupur R, Sarma KD, Gupta S, Puri SK, Launay D, Martin D