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It primarily arises from the catabolism of nutritional substrates such as phosphatidylcholine, choline, carnitine, betaine, dimethylglycine, and ergothioneine by the colonic microbiota (118)
Vitamin B12 is also critical for maintaining a healthy immune system and producing the mood-regulating chemical serotonin
Excessive intakes of animal protein, alcohol, added sugars, and processed foods have been tied to increased rates of hyperhomocysteinemia
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