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Indeed, transcriptomic profiling indicated that SLC7A11 inhibition by Erastin significantly upregulated the expression of gluataminolysis genes in A549 cells and LDHB KD A549 cells ( Figure 4a, b )

Four-week ketogenic diet intervention increased the transcription and histone acetylation of Grin2a and Grin2b in Shank3-deficient rats and ameliorate the decreased NMDAR synaptic function in PFC neurons

The answers below summarize what researchers and regulators know so far based on current clinical trials and public data

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Abbott BL, A-M C, Barnes Y, Marini F, Andreeff M , Sorrentino B

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