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Our research made it clear that, in comparison to the control group, the DOX groups ovaries downregulated SIRT1 expression, markedly elevated oxidative stress

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One of the forms of hypogonadism is called hypogonadotropic hypogonadism, where the organism suffers from hypogonadism due to under-functioning of the pituitary gland or hypothalamus

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using IGF-IR targeted therapies) showed promising anti-tumor effects [159, 160]