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While treatment with cisplatin alone enriched CSCs, WFA suppressed them by downregulating the stemness markers of CD44, CD24, CD34, CD117, and Oct4 and inhibiting Notch signaling factors of Notch1, Hes1, and Hey1, thereby preventing relapse and resistance (Sultana et al., 2021)

BMC Cancer 19 , 258 (2019)

The Glomerular Filtration Barrier: A Structural Target for Novel Kidney Therapies

This induces the recruitment of adaptive immune cells, including autoreactive CD8 + T-cells specific to melanocyte-derived proteins

171 WuX.WanM.LiG.XuZ.ChenC.LiuF.et al (2006)

Fundoplication surgery mechanically reinforces the lower esophageal sphincter through a surgical procedure