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Effects of environmental factors on APAP-induced mortality The above data demonstrate that our Drosophila -based system recapitulates studies performed in mice and demonstrates a similar pathologic mechanism for acetaminophen toxicity in Drosophila

Hashimoto S, Gon Y, Matsumoto K, Takeshita I, Horie T

Copper storage and transportation After uptake by the intestinal epithelial cells, copper is transported and exported into the bloodstream by the ATPase copper transporter 7 A (ATP7A) [18]