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1 Introduction Osteoarthritis (OA), is an extremely prevalent degenerative joint disease worldwide (Hunter and Bierma-Zeinstra, 2019)
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Gln expression has additionally been shown to increase under hyperammonemic conditions (45)
5-Amino-1MQ's mechanism centers on NNMT inhibition: NNMT inhibition : Selectively blocks NNMT with an IC50 of approximately 1.2 microM
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