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Purification uses amylose affinity columns

Dosage and Administration: For Parenteral Use Only after dilution or dissolution of compatible drugs, following manufacturer instructions: Do Not Use Directly : Not suitable for direct IV, IM, or SC injection without first being mixed with a solute

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Results vary between individuals

Following further optimization in the PC activation process, for 1 M (62.5 g/ml) PC, the optimal thrombin concentration was 85 nM or 3.12 g/ml (8.5% molar ratio or 5% w/w ratio to PC), whereas higher thrombin concentrations did not result in higher APC generation (see Supplementary Fig

The research was led by Isaac Harris, an associate professor in the Department of Biomedical Genetics, and colleagues including co-first authors Fabio Hecht and Marco Zocchi, both in the Harris Lab