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Clinical manifestations, diagnosis and epidemiological studies of ulcerative colitis UC, first described in 1859, is usually confined to the colon, where persistent superficial inflammation of the upper mucosa of the colon develops, leading to colonic ulceration and bleeding

Initial phase: Typically, during the initial phase, lipotropic injections may be administered more frequently, such as once or twice per week, for a few weeks

In leaner areas like the thigh, a 45-degree angle may be more appropriate

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