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The disorders main characteristic is that it is associated with previous chronic heavy cannabis use
The study adhered to the principles of the Declaration of Helsinki and was approved by the Institutional Ethics Committee of the Eye and Ears, Nose, and Throat Hospital, Fudan University (No.2024215)

P.et al (2019b)
Gating mechanism of the extracellular entry to the lipid pathway in a TMEM16 scramblase

The evidence outlined in the Sections Unlocking Melatonins Anti-Amyloidogenic Potential and Melatonins Neuroprotective Mechanisms against A toxicity indicates that melatonin exhibits anti-amyloidogenic properties and mitigates the neurotoxic effects of Aos, thereby potentially reducing the risk of developing AD or slowing its progression

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