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These features make it highly susceptible to oxidative damage due to a high concentration of easily oxidizable polyunsaturated fatty acids, iron and metals, as well as the neuronal metabolic rate which mediates the continuous production of ROS [31]

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N Engl J Med 369:17261734 Bakker J, Gris P, Coffernils M, Kahn RJ, Vincent JL (1996) Serial blood lactate levels can predict the development of multiple organ failure following septic shock

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P., et al., An Integrated MultiOmic Approach to Assess Radiation Injury on the HostMicrobiome Axis, Radiation Research 186, no