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Various forms of treatment, the most effective regimen at the time -- interferon alone, interferon plus ribavirin, peginterferon alone, peginterferon plus ribavirin -- were administered to 60 patients diagnosed with acute hepatitis C

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These virus-induced vesicles could damage mitochondrial membrane integrity, release mt-DNA into circulation, compromise innate immunity, and trigger an exacerbated pro-inflammatory response in COVID-19 patients 164
