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Description
Atherosclerosis progression, as a chronic inflammatory mechanism, is characterized by immune system dysregulation associated with increased pro-inflammatory cytokine production, including interleukin 6 (IL-6), tumor necrosis factor- (TNF-), and IL-1, as well as pattern recognition receptor proteins like CRP (170, 261267)

Antioxidants such as glutathione help neutralize free radicals and influence pigment production pathways

Bacterial translocationImpact on the adipocyte compartment (in Eng)

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Further studies on tissue/cell type-specific UPR are warranted to provide more comprehensive evidence-based support for charting the panorama of vitiligo pathogenesis
