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Redox modulation of the apoptogenic activity of thapsigargin

Exagamglogene autotemcel (exa-cel, formerly CTX001) CRISPR-Cas9 gene therapy was reported to increase fetal hemoglobin production through suppression of BCL11A expression and transfusion-independence in a 19-year-old female adult with TDT (beta 0 /beta + genotype) in a case report (183)

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At the same time, the other group of D-gal-treated mice and the control group of mice were given distilled water, and the fourth group received PQQ (100 gkg 1 d 1 ) only