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For sublingual troches, this is particularly problematic because absorbed moisture can initiate the dissolution process prematurely, causing the troche to become sticky, soft, or crumbly before use

Festoff et al., 2016

Cerebellum 2009

It is not recommended to combine it in the same routine with retinol or strong exfoliating acids unless skin tolerance is confirmed

Part I: heterocyclic modifications of the core structure
