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Due to the low membrane permeability of itaconate [47], the micromolar concentration of extracellular itaconate applied in the present study appears to be insufficient to cause sufficiently high cellular concentrations that are able to affect the metabolic processes investigated

doi: 10.3389/fneur.2017.00037 11

[Google Scholar] 16.Tricco AC, Lillie E, Zarin W, et al

Interaction between p53 N terminus and core domain regulates specific and nonspecific DNA binding