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Long-term human safety data does not exist, which is the main caution
Starting or restarting any peptide protocol requires a physician evaluation, appropriate lab work, and a clinical rationale
The process is fast and highly predictable
They target different parts of health and recovery
Conducting future studies with randomized controlled design, sufficient sample size and on patients with normal level of folate and B12 is highly recommended to clarify the effect of B12 supplementation on tHcy concentrations in ESRD
