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Additionally, tirzepatide may reduce appetite, which could lead to decreased food and fluid intake in some patients, potentially contributing to constipation risk
Specifically, SIRT1, SIRT3, and SIRT5 protect the cell from ROS, and SIRT2, SIRT6, and SIRT7 modulate oxidative stress 138,139
Do not use normal saline
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Bjrklund G, Tinkov AA, Hosnedlov B, Kizek R, Ajsuvakova OP, Chirumbolo S, Skalnaya MG, Peana M, Dadar M, El-Ansary A, Qasem H, Adams JB, Aaseth J, Skalny AV
Therefore, there is an urgent need to develop effective therapeutic interventions for DbCM
