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[DOI] [PMC free article] [PubMed] [Google Scholar] 282.Vassar R

TCA Cycle Intermediates and Nuclear Function Similar to the nuclear localization of the pyruvate dehydrogenase complex (PDHc), at least two enzymes and enzyme complexes of the TCA cycle are found in the nucleus

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The negative feedback mechanism in this cycle is catalyzed by two enzymes, glycine N-methyltransferase that converts s-adenosylmethionine to s-adenosylhomocysteine and s-adenosylhomocysteine hydrolase that converts s-adenosylhomocysteine to homocysteine [52]

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