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Dysregulation of Th17 activity has been implicated in the pathogenesis of inflammatory and autoimmune disorders, including colitis

It is converted to coenzyme B12 in the body and in this form facilitates the conversion of homocysteine to methionine (methylcobalamin) and plays an important role in converting methylmalonyl-coenzyme A to succinyl-Co-A (fatty acid and amino acid metabolism)

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