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This product is supplied exclusively for laboratory research and must not be used for human or veterinary applications

Leg muscle cramps or involuntary contractions of your legs and feet can cause serious pain, sleep disruption patterns, and health issues.

Here, through a proteomic screen of serum from AQP4-IgG-positive NMOSD patients and a control cohort, we observed a significant downregulation of Insulin-like growth factor 2 (IGF-2) in the serum of AQP4-IgG-positive NMOSD patients and correlated with disease severity

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