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Furthermore, ELISA results indicated that petroleum ether extracts decreased the elevated levels of IBA-1, IL-1, A 1-42 , and p-tau in the hippocampus and cortex following LPS treatment (Wang et al., 2018

doi: 10.1002/(SICI)1096-9861(20000605)421:3 3.0.CO;2-9

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Because of its insolubility and non-crystallinity, PrP Sc aggregates constitute challenging targets for solution NMR or X-ray crystallography