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In such cases, it is recommended that the patient be weaned off the medication and then slowly initiated on a replacement
3.5.2 Activation of the Keap1Nrf2 pathway and detoxification ITCs are potent activators of the Keap1Nrf2 signaling pathway, which upregulates cytoprotective genes
According to Miller et al
Rats were not prescreened
doi: 10.1186/s12943-017-0753-1
