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doi: 10.2217/nnm.14.179

Among the 40 patients evaluable for response, 18 patients met the 12-week PFS primary endpoint, with one patient achieving a PR, and 27 patients achieving SD as the best response (Scott et al., 2022)

Randomized placebo-controlled trials found GSH improved oxygenation and clinical parameters in CF, although the effect may not be due to correction of oxidant/antioxidant balance

Niacinamide's calming properties may actually help offset any irritation from copper peptides

Zamanian et al

The four tested compounds used to activate GPx4 are as follows: ferrostatin, lapatinib, liproxstatin-1, and PKUMDL-LDL-102