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CAR-T cell combination therapy with allo-HSCT Allogeneic hematopoietic cell transplantation (allo-HCT) and CAR-T cell therapy are considered powerful adoptive cellular therapy strategies (ACT)

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In the liver cholecalciferols are hydroxylated at the 25 position by a specific vitamin D 25-hydroxylase generating 25-hydroxy-D 3 [25-(OH)D 3 : more commonly called calcidiol]

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A total of 2,875 negative ion-mode metabolites were identified, including 153 significantly over-expressed metabolites and 232 significantly downregulated metabolites (Figure 3B)