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DP3 [t R = 44.2 min], DP4 [t R = 31.6 min] and DP5 [t R = 5.8 min t R = 6.9 min] were minor compounds

Other investigators have attempted to facilitate the availability of central brain-derived neurotrophic factor (BDNF) with injections of human BDNF directly into the patients brain with minimal positive results [17]

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One theory put forward by Clevers et al