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Mild side effects may include temporary soreness at the injection site, which typically resolves quickly
However, if all sources of mitochondrial pyruvate are impeded, hepatocytes switch to metabolism of amino acids to maintain flux at the cost of reduced synthesis of the antioxidant glutathione
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[4] [78] [96] [75] A placebo-controlled clinical trial of NADH (which excluded NADH precursors) in people with Parkinson's failed to show any effect
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