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FIGURE 2 2.2 Mitochondrial dysfunction caused by oxidative stress in diabetes Mitochondria, also known as the energy house [39], are highly dynamic double-membrane organelles that produce adenosine triphosphate (ATP), the energy that the body requires (Newmeyer and Ferguson-Miller, 2003)

Injectable glutathione bypasses the digestive system, where oral glutathione undergoes significant breakdown by stomach acid and intestinal enzymes

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Minocycline, beyond suppressing matrix metalloproteinase-9 (MMP-9), interferes with microglial activation and NLRP3 inflammasome assembly, thereby attenuating neuroinflammation 19 (Fig

Chemicals and Reagents NAC, reduced GSH, glutathione peroxidase (GPx), and Tris hydrochloride were obtained from Sigma-Aldrich (St

GABA signaling: A route to new pancreatic cells