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Increasing levels of VitB12 in humans have been shown to lead to a decline in 24-h mean melatonin levels and nocturnal melatonin levels during bright-light exposure, thereby disrupting the sleep-wake cycle toward increased alertness and decreased sleep duration [21, 38]
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The clinical trials showed that at least four weeks at each dose level is necessary for the body to adapt
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A noticeable loss of interest in activities, hobbies, or social engagements underscores the cognitive impact of the disorder
