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Macrophage polarization can be categorized into M1 (classically activated macrophages or pro-inflammatory) and M2 (alternatively activated macrophages or anti-inflammatory) macrophages based on the arginine metabolism (Lumeng et al., 2007)

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Bone broth is considered a powerful agent in detoxification because it helps the digestive system expel waste and promotes the livers ability to remove toxins

Interestingly, c-myc plays a crucial role in orchestrating the sequential activation of glycolysis and glutaminolysis, as well as FA and PG synthesis (FA synthesis follows glycolysis and glutaminolysis), thereby allowing tumor cells to balance access to the nutrients with the stoichiometric production of substances [86]

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