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Patients with a history of cobalt allergy may be at increased risk, as all cobalamins (including hydroxocobalamin and cyanocobalamin) contain a cobalt atom in their molecular structure

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While large-scale human trials remain limited, the existing research paints a promising picture
Side effects can include pain or redness at the injection site, mild diarrhea, itching, or a feeling of swelling all over the body
Ritzel et al., 2015

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