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ASS1, a urea cycle enzyme that catalyzes argininosuccinate synthesis from citrulline and aspartate, facilitates ammonia detoxification (84)

Involvement of IGF-1R regulation by miR-515-5p modifies breast cancer risk among BRCA1 carriers

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Biomarkers serve as the bridge between mechanistic discovery and clinical translation, enabling researchers to assess safety, efficacy, and disease modification

Informed consent: This work did not involve the use of animals and therefore informed consent was not required

Proc Natl Acad Sci U S A 106(4):12851290