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It's this very question that pushes scientists to investigate underlying factors like inflammation and, you guessed it, oxidative stress

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Alcohol is a triple threat: it contains histamine (especially wine and beer), it inhibits DAO activity, and it increases intestinal permeability (allowing more histamine to enter circulation)

THE GH, IGF-1, AND INSULIN INTERPLAY IN TYPE 1 DIABETES MELLITUS To understand the dynamics of this interplay in T1DM, one must go back to the relation between portal insulin and GHR expression on hepatocytes, which was so cleverly addressed by Leung et al

doi: 10.1021/acs.jproteome.1c00851

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